Carol Bennett-Clarke, Ph.D
Emeritus Professor
Office:聽181 Block Health Science Building
Tel: 419-383-4115
贰尘补颈濒:听carol.bennett-clarke@utoledo.edu
Education:
1974:聽聽B.S. (Biology),聽Denison University, Granville, Ohio
1980:聽聽Ph.D. (Anatomy),聽University of Rochester, School of Medicine and Dentistry, Rochester, New York聽
1980-1981: 聽Post Doctoral Fellowship University of Rochester, Center for Brain Research聽
1981-1984:聽聽University of Rochester, Neuroendocrine Unit
2000 -2001聽聽Teaching Fellowship, Medical College of Ohio, Toledo Ohio
Research Interests:
My first ten years in the department I was a member of a busy collaborative research team. My bench research program within the group was related to the development and plasticity of sensory projections in the central nervous system. In particular, my work focused on the role that neurochemicals play during the elongation and arborization of axonal processes from neurons of
sensory thalamic nuclei to the cerebral cortex. Seminal work in our lab found that one specific neurotransmitter, serotonin, as well as, one class of it鈥檚 receptors and it鈥檚 high affinity uptake site are transiently expressed during development in the sensory cortices and play a significant role in the modeling of these thalamocortical axonal arbors.
My current research interests are in the field of education.聽 Recent work with my colleagues has focused on the development and use of plastinated specimens as a teaching tool in the human dissection laboratory setting.
Educational Scholarship:
In the late 1990s I began working with two other members of the Department of Neurosciences, Mark Hankin and Dennis Morse, in
collaboration with a medical聽illustrator Roy Schneider and the Center for Creative Instruction (CCI) to develop educational software entitled Anatomy Revealed. The premise for this software was to provide a digital interface for a 鈥渕elt away鈥�
approach to human dissection.聽 Digital photography of carefully orchestrated dissections
in the cadaver lab were used to captured images that were enhanced and combined to
create a permanent record that students can review repeatedly. Several years of work
resulted in anaward-winning multidisciplinary educational software product.聽 Six Anatomy
Revealed modules (presented on four CD-ROMs) have been produced for use in our medical
school curriculum.聽 These modules explore in detail the anatomy of the head and contain
numerous related clinical correlations.In 2003, McGraw-Hill Publishing approached the authors of 聽about creating a version of the software for undergraduate students to use.聽 Over the course of the several years, the
authors have worked create a widely successful CD which covers all body systems. The authors and publishers expect the organ systems-based APR to set a new standard for computer-based learning in the field.
Teaching Interests:
For the last ten years I have played a very active role in the redesign and implementation of multiple changes in the preclinical curriculum in the school of medicine.聽 I currently serve the institution as Associate Dean for the Preclinical Curriculum. I also serve as the block director for a first year curricular block entitled, 鈥淗uman Structure and Development鈥�.聽 This is a 15-week core course currently team taught for approximately 175 medical students yearly.聽 I also provide lectures in the Neuroscience block for medical students and am a primary instructor in the Gross Anatomy course for Physicians Assistants (College of Allied Health).
I serve as the Program Director for students in the Masters of Science in Biomedical Sciences in Medical Science Program. The program is designed to improve the foundational knowledge of students who wish to gain admission into a medical school. As Program Director I am responsible for the admissions process and organization of the one year curriculum.聽 The 40 students in the program enroll in 40 didactic credits. I also coordinate the MEDStart program which is 2-week experience offered during the summer for students who have gained early admission to the College of Medicine.Publications:
Schneider R, Hankin MH, Morse聽DE, and Bennett-Clarke CA.聽 (2007) Anatomy and Physiology聽Revealed,聽 All systems are included on a single. (Undergraduate聽Edition) (CD-ROM, ver 2.0).聽 McGraw-Hill Publishers.
Schneider R, Hankin MH, Morse聽DE, and Bennett-Clarke CA.聽 (2004) Anatomy Revealed: Cranial聽Cavity. (Professional Edition) (CD-ROM, ver 1.0).聽 Medical College of聽Ohio, Toledo, Ohio.
Schneider R, MH Hankin, DE聽Morse, CA Bennett-Clarke. Anatomy Revealed 鈥� Nasal and Oral Cavities聽(CD-ROM, v. 1.0). Medical University of Ohio, Toledo, OH, 2003.
Schneider R, MH Hankin, DE聽Morse, CA Bennett-Clarke. Anatomy Revealed 鈥� Orbit (CD-ROM, v. 1.0). Medical University of Ohio, Toledo, OH, 2000.
Schneider R, MH Hankin, DE聽Morse, CA Bennett-Clarke. Anatomy Revealed 鈥� Face (CD-ROM, v. 2.0).聽Medical University of Ohio, Toledo, OH, 1999.
Boylan, C.B., Kesterson, K.L., 叠别苍苍别迟迟-颁濒补谤办别,听颁.础., Chiaia, N.L. and Rhoades, R.W. (2001) Neither peripheral nerve input nor cortical NMDA receptor activity are necessary for recovery of a disrupted barrel pattern in rat somatosensory cortex.聽 Dev. Brain Res. 129:95-106.聽
Boylan, C.B., 叠别苍苍别迟迟-颁濒补谤办别,听颁.础., Crissman, R.S., Mooney, R.D., and Rhoades, R.W. (2000)聽Clorgyline treatment elevates cortical serotonin and temporarily disrupts the vibrissae-related pattern in rat somatosensory cortex. J. Comp. Neurol. 427:139-149.
Young-Davies, C.L., 叠别苍苍别迟迟-颁濒补谤办别,听颁.础., Lane, R.D., and Rhoades, RW (2000) Selective facilitation of聽serotonin 1B receptor causes disorganization of thalamic afferent and聽barrels in somatosensory cortex of rat. J Comp. Neurol. 425:130-138.
Lieske, V., 叠别苍苍别迟迟-颁濒补谤办别,听颁.础., and Rhoades, R.W. (1999) Effects of 5-HT on neurite outgrowth聽from thalamic neurons in vitro. Neuroscience, 11: 179-185.
Rhoades, R.W., Chiaia, N.L.,聽Lane, R.D., and Bennett-Clarke, C.A. (1998) Effect of activity聽blockade on changes in vibrissae-related patterns in the rat鈥檚 primary聽somatosensory cortex induced by serotonin depletion. J. Comp. Neurol.,聽402:276-283.
Bennett-Clarke, C.A., Chiaia, N.L., and Rhoades, R.W. (1997) Contributions of raphe-cortical and thalamocortical axons to the transient somatotopic pattern of serotonin immunoreactivity in rat cortex.聽 Somatosen. Motor Res., 14: 27-33.