兔子先生传媒文化作品

1975 B.S. in Chemical Engineering, Andhra University, India听
1977 M.S.Ch.E., Indian Institute of Technology, Kanpur听
1983 Ph.D. in Chemical Engineering, State University of New York at Buffalo

Our current research activities are mainly in three areas: (1) using ionic liquids (ILs) as 鈥済reen solvents鈥�; (2) biocatalysis; and (3) colloids and surface phenomena. In the first area, we are interested in the use of ILs (i) for pretreatment of biomass to achieve enhanced enzymatic saccharification for fuel and chemical production, and (ii) as extracting solvents for bioproducts. In the area of biocatalysis, we are using immobilized enzyme catalysis and fermentations involving native and genetically engineered microorganisms (GMOs). In the third area, we are applying the principles of colloidal and surface phenomena in separation processes. Our applications include protein crystal nucleation kinetics and membrane separation processes (facilitated transport & active transport).

1. Alipour S., Relue, P., Viamajala, S., and Varanasi, S., High Yield 5-Hydroxymethylfurfural Production from Biomass Sugar at Facile Reaction Conditions: Implementation of Simultaneous-Isomerization-and-Reactive Extraction, Back-Extraction, and Dehydration, Energy and Environmental Science (under review).
2. Maddi B, Viamajala S, Varanasi S. 2013. 鈥淧yrolytic fractionation: A promising thermo-chemical technique for processing oleaginous (algal) biomass鈥� Energy and Environmental Science (under review).
3. Mudiyanselage A. Y., Viamajala S., Varanasi, S., and Yamamoto K., 鈥淎 simple ring-closing metathesis approach for synthesis of nylon 11鈥�13 precursors from oleic acid鈥�, ChemSusChem (under review)
4. Bin Li, S. Varanasi and P. Relue, 鈥淗igh yield aldose鈥搆etose transformation for isolation and facile conversion of biomass sugar to furan鈥�, Green Chemistry, 15, (2013), 2149-2157.
5. Bin Li, P. Relue, and S. Varanasi, Simultaneous isomerization and reactive extraction of biomass sugars for high yield production of ketose sugars, Green Chemistry, 14 (2012) 2436-2444.
6. Y. Dawei, K. Rao, P. Relue and S. Varanasi, A viable method and configuration for fermenting biomass sugars to ethanol using native Saccharomyces cerevisiae, Bioresource Technology, 117(2012) 92-98
7. B. Maddi, S. Viamajala, and S. Varanasi 鈥淐omparative study of pyrolysis of algal biomass from natural lake blooms with lignocellulosic biomass鈥� Bioresource Technology, 102 (2011) 11018鈥�11026
8. Kripa Rao, Y. Dawei, P. Relue and S. Varanasi 鈥淔ermentation of biomass sugars to ethanol using native industrial yeast strains鈥� Bioresource Technology, 102 (2011) 3246鈥�3253
9. P.Li, Q. Zhao, J. L. Anderson, S. Varanasi and M. Coleman, Synthesis of coplyimides based on room temperature ionic liquids, Journal of Polymer Science: Part A: Polymer Chemistry, vol 48, 4036-4046, (2010)
10. R. A. Gosavi, V. Bhamidi, S. Varanasi, and C. A. Schall, 鈥淏eneficial Effect of Solubility Enhancers on Protein Crystal Nucleation and Growth, Langmuir, vol. 25, pp.4579 鈥� 4587 (2009)
11. F. Zhao, T.K. Ponnaiyan, C. M. Graham, C.A. Schall, S. Varanasi, and J. Anderson 鈥淒etermination of ethanol in ionic liquids using headspace solidphase microextraction鈥揼as chromatography, Analytical and Bio analytical Chemistry, 392 pp 1271-1275, 2008.
12. K. Rao, S. Chelikani, P. Relue, and S. Varanasi, 鈥淎 Novel technique for Optimizing the Simultaneous-Isomerization-and-Fermentation (SIF) Approach of Converting Xylose to Ethanol, Applied Biochemistry and Biotechnology, 146, pp. 101-117 (2008)
13. Anantharam P. Dadi, C. A. Schall and S. Varanasi 鈥淢itigation of Cellulose Recalcitrance to Enzymatic Hydrolysis by Ionic Liquid Pretreatment鈥� Applied Biochemistry and Biotechnology, 136-140, pp. 407-421(2007)
14. K.Rao,V. Chaudari, D.-S. Kim, and S. Varanasi, 鈥淓nhanced Ethanol Fermentation of Brewery Waste Water Using the Genetically Modified Strain, E. coli KO11, Applied Microbiology and Biotechnology, 74, pp.50-60 (2007).
15. Anantharam P. Dadi, S. Varanasi and C. A. Schall 鈥淓nhancement of cellulose saccharification Kinetics using an ionic liquid pretreatment step鈥�, Biotechnology and Bioengineering, vol. 95, pp 904-910 (2006)

1. S. Varanasi, C. Schall, A. P. Dadi, J. Anderson, K.Rao, P. Paripati, and G. Kumar, 鈥淏iomass Pretreatment鈥�, US patent # 8,546,109; issued: October 1, 2013 (Divisional Patent)
2. S. Varanasi, K. Rao, P.Relue, and D. Yuan 鈥淢ethods for fermentation of xylose and hexose sugars,鈥� US Patent # 8,507,232, issued August 13, 2013
3. S. Varanasi, C. Schall and A.P. Dadi 鈥淧roduction of ethanol from saccharified cellulose following Ionic Liquid pretreatment鈥�, US patent # 8,236,536, issued: August 7, 2012
4. S. Varanasi, C. Schall, A. P. Dadi, J. Anderson, K.Rao, P. Paripati, and G. Kumar, 鈥淏iomass pretreatment鈥�, US patent # 8,030,030, issued: October 4, 2011
5. S. Varanasi, C. Schall and A. P. Dadi 鈥淪accharifying Cellulose鈥�, US patent # 7,674,608, Issued: March 9, 2010
6. J. Byers, R. Fournier, S. Varanasi, 鈥淢ethod of Producing Products with a bilayer pellet containing a coimmobilized enzyme system that maintains a pH difference鈥�, US Patent # 5,397,700
7. J. Byers, R. Fournier, S. Varanasi, 鈥淏ilayer pellet containing immobilized xylose isomerase and urease for the simultaneous isomerization and fermentation of xylose to ethanol鈥�, US Patent # 5,254,468
8. S. Varanasi, K. Rao, P.Relue, and D. Yuan 鈥淢ethods for fermentation of xylose and hexose sugars,鈥� U.S. Patent Application 20130330800; US Divisional Patent filed August 12, 2013
9. B. Li, S. Varanasi and P. Relue. 鈥淎ldose-ketose transformation for separation and/or chemical conversion of C6 and C5 sugars from biomass materials鈥�. U.S. Patent Application 20130074397, PCT/US11/33030, November 7, 2012.
10. G. Lipscomb, S. Varanasi, P. Paripati, A. P. Dadi, 鈥淚onic liquid Recovery and Purification in Biomass Pretreatment Processes鈥� U.S. Patent Application 20130292331, November 7, 2013
11. G. Lipscomb, S. Varanasi, P. Paripati, A. P. Dadi, 鈥淟iquid Recovery and Purification in Biomass Pretreatment Processes鈥� U.S. Patent Application 20120298584, November 29, 2012
12. S. Alipour, B. Li, S. Varanasi, P. Relue, and S. Viamajala, 鈥淣ew methods for high yield production of furans from biomass sugars at mild operating conditions,鈥� US Provisional Patent filed 11/1/2013
13. Maddi B.; Viamajala, S.; Varanasi, S. 2011. Thermal Fractionation of biomass of non-lignocellulosic origin for multiple high-quality biofuels (US Patent Pending) #13/294510.
14. H. Shao, A. Vadlamani, S. Viamajala, S. Varanasi and P. Relue. 鈥淓nzymatic digestion of microalgal biomass for lipid, sugar, and protein recovery,鈥� Provisional US Patent application, D2013-77, filed April 29, 2013.
15. Yamamoto K., Viamajala S., Varanasi S., Nguyen K., Abel G., Mudiyanselage A. Y., Cross Metathesis Approach to C12 and C13 Fatty-Chain Amino Esters from Oleic Acid Derivatives, (US Patent Pending) #1-56166/D2014-06
16. Yamamoto K., Viamajala S., Varanasi S., Nguyen K., Mudiyanselage A. Y Ring Closing Metathesis Approach To Produce Precursors Of Nylon 11, 12, And 13 From Oleic Acid (US Patent Pending)

Received funded from National Science Foundation, US DOE, USDA, US Air Force Office, Ohio Third Frontier Commission; Ohio Coal Development Office, DOE-SBIR, and USDA-SBIR; some recent grants are listed below.

The Ionic Liquid Pretreatment technology developed for lignocellulosic biomass processing is licensed to industry and is being commercialized.

1. 鈥淚ntegration of Nutrient and Water Recycling for Sustainable Algal Biorefineries.鈥� PI: Viamajala S,Co-Is: Varanasi S, Gerlach R, Characklis W, Hamud I, Johnson R, Fields M, Peyton B. Funded by the US Department of Energy, Office of the Biomass Program. Collaborating Institutions 鈥� 兔子先生传媒文化作品, Montana State University, University of North Carolina, City of Logan (Environmental Department) and Advanced Algae Solutions, LLC. Lead Institution 鈥� 兔子先生传媒文化作品. Total project award: $2,999,934. UT award: $1,140,508. Role: Project Co-PI. September 2012. (Duration 鈥� 3 yrs)
2. 鈥淪EP Collaborative: Alkaliphilic microalgae-based sustainable & scalable processes for renewable fuels and products.鈥� PI: Viamajala S,Co-Is: Gerlach R, Characklis W, Varanasi S, Yamamoto K, Fields M, Peyton B. Agency: National Science Foundation鈥檚 (NSF) Sustainable Energy Pathways (SEP) Program. Collaborating Institutions 鈥� The University of Toledo, Montana State University and University of North Carolina. Lead Institution 鈥� University of Toledo. Total project award: $1,900,000. UT award: $950,000. August 2012. (Duration 鈥� 4 yrs)
3. 鈥淐enter for Algal Engineering Research and Commercialization.鈥� Bayless D, Viamajala S, Stuart B, Varanasi S et al. Agency: Ohio Third Frontier鈥檚 Wright Project program. Collaborating Institutions 鈥� Ohio University and 兔子先生传媒文化作品. Lead Institution: Ohio University. Total project award: $2,970,063. UT award: $1,027,061; Role: Co-PI for UT award. May 2010. (Duration 鈥� 3 yrs)
4. 鈥淢RI-R2: Acquisition of a suite of analytical instrumentation essential for investigating fuel, chemical and polymer production from biomass.鈥� PI: Varanasi S, Co-Is: Lapitsky Y, Viamajala S, Anderson J, Schall C., Funded by the NSF Division of Chemical, Bioengineering, Environmental, and Transport Systems (CBET) Major Research Instrumentation (MRI) program. Award: $992,690. April 2010 (Duration 鈥� 3 yrs)
5. Simultaneous Isomerization and Reactive Extraction of Biomass Sugars for Efficient Furan Production via High Yield Ketose Intermediate (PI: Sasidhar Varanasi Co-I: P. Relue) Award Period: August, 2012 鈥� August 2015 Award: $309,523 Agency: National Science Foundation.
6. 鈥淧ilot Scale demonstration of cellulosic-ethanol process鈥� SuGanit Systems, Inc and University of Toledo (UT subcontract $250,000; PI: S. Varanasi), 2011 Third Frontier Advanced Energy Program - State of Ohio, Total award $1,000,000, April 2011 鈥� March 2013.
7. 鈥淧ilot Scale demonstration of cellulosic-ethanol process鈥� (PI: S. Varanasi), 2011-Wright Projects Program 鈥� Ohio Department of Development, Total award $1,000,000, April 2011 鈥� March 2014.
8. 鈥淒irect Catalytic Conversion of Lignin to Aromatic Chemicals鈥� (PI: Mark Mason, Co-I: Sasidhar Varanasi) subcontract from SuGanit Systems Inc.on Department of Energy- SBIR Phase 1; award period: 4/18/2012- 11/19/2012 Award : $150,000; Subcontarct $50,000.
9. Alkaliphilic microalgae-based processes for renewable fuels and chemicals, (PI: Sridhar Viamajala, Co-Is: Sasidhar Varanasi, Kana Yamomoto; Dragan Isailovic) Interdisciplinary Research Initiation Awards Program, Office of Research and Sponsored Programs, The University of Toledo, $100,000 Duration: May 2012-April 2013
10. A facile pretreatment strategy for recovering sugars and lignin effectively from a variety of lignocellulosic feedstocks (PI:S. Varanasi Co-I: C. Schall) Award Period: September, 2009 鈥� August 2012 Award: $310,945 Agency: National Science Foundation
11. Development of co-immobilized enzyme pellet to replace GMO鈥檚 for cellulosic ethanol听production (UT faculty: PI: S. Varanasi, Co-I: P.Relue) Award Period: June 2009 鈥� June 2011 Award: Total award $80,000 UT subcontract from SuGanti Systems: $36,000, Agency: US Department of Agriculture, SBIR-Phase 1
12. Renewable Hydrocarbon Fuels from Algae, (PI: Sasidhar Varanasi); Award Duration: 6/05/2009 鈥� 12/13/2011, Amount: $138, 461, Agency: US Air Force Office of Research via a subcontract through Center for Innovative Food Technology.
13. Scale-up of Ionic Liquid Recovery Methods following Biomass Pretreatment ,Award Period: September. 2009 鈥� August 2011 Amount: $228,516 Agency: Suganit systems, inc. (subcontract on Department of Energy SBIR Phase II; Total award $750,000)
14. Lab-scale set-up to convert biomass into valuable products through integral pyrolysis and steam reformation units, Award Period: January 2010 鈥� June 2010 Amount $50,000 Agency: REII (subcontract on a Department of Energy pilot scale Demonstration grant) (PI: S. Varanasi, Co-I: G.G. Lipscomb)
15. A novel simultaneous-saccharification-fermentation strategy for efficient co-fermentation of C5 and C6 sugars using native, non-GMO yeasts, PI: S Varanasi, Co-I: P. Relue, Department of Energy- Office of Biomass Program, $500,000, February 2009 鈥� January 2012.
16. 鈥淪cale up of Cellulosic Ethanol Process Based on Novel Biomass Pretreatment and Efficient Co-Fermentation,鈥� SuGanit Systems, Inc and University of Toledo (UT subcontract $505,000; PI: Sasidhar Varanasi, Co-Is: C. Schall, P. Relue, and J. Anderson), 2009 Third Frontier Advanced Energy Program - State of Ohio, $999,900, April 2009 鈥� March 2012.
17. 鈥淎 Novel Cellulosic Biomass Fermentation Process for Ethanol Production,鈥� PI: S. Varanasi, Co-Is P. Relue, P. Paripati, and G. Kumar, 2008 Third Frontier Advanced Energy Program 鈥� State of Ohio, $250,000, June 2008 鈥� August 2009.
18. Total Award: $100,000 (Sub-contract $33,000); Award Period: 06/2008- 12/2008; Project Title: Feasibility of commercialization of a pretreatment process for enhanced biomass saccharification (Sub-contractor to SuGanit Systems.with C. Schall); Sponsor: Department of Energy - SBIR (Phase 1)